the role of her2 in breast cancer and how it can influence treatment? And how we can use bioinformatics to learn more about it in individuals

the role of her2 in breast cancer and how it can influence treatment? And how we can use bioinformatics to learn more about it in individuals

HER2 breast cancer; predictive and prognostic biomarker

Population frequency

Risk factors – epidemiology

Gene expression CNV / microarray

Detections in DNA and Protein

Treatments

Use of Herceptin

So it’s basically just looking at the role of her2 in breast cancer and how it can influence treatment? And how we can use bioinformatics to learn more about it in individuals?

You need to download R software suite

And run through the whole programme

Analyse the data and relate it to HER 2 background info

It’s basically showing that her- had a higher peak of combined genes compared to her+ which had less overall, but had a separate peak for the HER2 gene that was not seen in HER-

So I kinda interpreted that as the fact that her- has to have multiple drivers whether that be er or pr or something else, whereas her2 can literally just her2 pr- er- and be caused only by up regulation of HER2 (which would be that one other peak on the graph)

To demonstrate the bioinformatics that can be used to analyse the cases.

It’s an essay on her2 but I believe you are meant to talk about the methods, then results which would be the case study we did and the questions we completed

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